The muscle must be put under tension for a quality period of time, preferably through a full range of motion. If you're using the bench press, there's little point in doing 3-4 reps at a really heavy weight with poor form, and partial ROM. Muscle tissue would be broken down better be a slower lowering phase so each rep lasts 3-4 secs so for a set of 10-12 through full ROM you're talking about the muscle being under quality stress for up to 45 secs.
Focus on tension, stressing the muscle properly, rather than the heavy load, you're gains will be better.

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